Effect of Systemic Antibiotic Therapy on Postoperative Complications in Patients Undergoing Wisdom Teeth Removal Surgery.

• Status: Recruiting
• Trial end date: 2022-03-01
• Target enrollment: 0
• Participant gender: All

Summary

59 medically healthy patients, who are scheduled for third molar extraction surgery and give informed consent for the trial, are operated using a split-mouth technique.

One group of patients will be assigned to the test group (Amoxilan) for the first surgery and to the control group (placebo) for the second surgery, and vice versa, according to randomisation.

Patients receive 8 capsules Amoxilan or placebo (according to randomisation) perioperatively, and 6 capsules Amoxilan/placebo per day for 3 days postoperativeley.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Graz

Criteria

Inclusion Criteria:

• Symptom-free, bilaterally located third molars

• Medically healthy patient ≥ 16 years

• No allergies/intolerances against the investigational product/placebo

• Informed consent

Exclusion Criteria:

• General contraindications to wisdom tooth extraction surgery

• (Former) heavy smoking

• Use of antibiotics within the last three months or patients requiring antibiotic treatment prior to surgery

• (Planned) Pregnancy/lactating