Effect of Tadalafil on Exercise Capacity in Pediatric Fontan Patients
Status:
Completed
Trial end date:
2014-02-01
Target enrollment:
Participant gender:
Summary
This pilot study is aimed at assessing the short-term effects of Tadalafil on the hemodynamic
response to exercise and exercise capacity in patients with Fontan circulation. Data
regarding effect size and drug tolerability will be used in the design of a randomized
multicenter trial. The long-term goal of this investigation is to systematically evaluate the
effect of tadalafil therapy on exercise performance, quality of life, and delay of functional
deterioration in patients with single ventricle physiology.