Effect of Terlipressinum on the Portal Vein Pressure of Patients With Liver Tumor After Liver Resection

• Status: Unknown status
• Trial end date: 2018-12-30
• Target enrollment: 0
• Participant gender: All

Summary

In this study, investigators aim to screen out the patients with portal hypertension by monitoring intraoperative PVP, and to decide the effect of Terlipressinum on the portal pressure after liver resection.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai Zhongshan Hospital
• Treatments: Lypressin; Terlipressin

Criteria

Inclusion Criteria:

1. Patients who receives liver resection.

2. PVP is more than 12mmHg in 5 minutes after liver resection.

Exclusion Criteria:

1. Age: <18, >75;

2. Portal vein tumor thrombus is confirmed by preoperative assays;

3. Obstruction of biliary tract;

4. Active hepatitis;

5. Previous history of myocardial infarction;

6. Previous history of chronic kidney disease;

7. Severe arrhythmia;

8. Any other contraindications of the Terlipressinum.