Effect of Thoracic Epidural Analgesia on Intravenous Closed-Loop Anesthesia
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
The association of general anesthesia and of thoracic epidural anesthesia is used in thoracic
surgery with a demonstrated benefit on the risk of postoperative respiratory complications.
The objective of the study is to analyze the influence of thoracic epidural administration of
chirocaine (5 mg/ml) on the administration of anesthetic agents (propofol and remifentanil),
these drugs being administrated using a closed-loop system with the Bispectral Index as the
controller.
Two groups of patients are compared:
- one group will receive general anesthesia and thoracic epidural administration of
saline. Chirocaine will be administered before patient's awakening,
- one group will receive general anesthesia and thoracic epidural administration of
chirocaine (5 mg/ml).
In both groups, the closed-loop system ensures that le depth of anesthesia is similar in both
groups.