Effect of Tranexamic Acid on Prevention of Recurrence of Hemoptysis

• Status: Withdrawn
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Hemoptysis is one of the serious complication of many pulmonary diseases. Upto now, there is no proven medical treatment in recurrence of hemoptysis. The investigators will conduct a randomized, placebo controlled trial of tranexamic acid, which can reduce the recurrence of hemoptysis.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• age: >=20 and <=75

• ER visit or admission for hemoptysis

• no evidence of hemoptysis on screening

Exclusion Criteria:

• anticoagulation treatment

• Cr >= 2.0 mg/dL or urinary protein >= 2+ or who received renal replacement treatment

• hepatic failure: total bilirubin >= 1.5 mg/dL or AST or ALT >= 1.5 of upper normal limit level

• hypersensitivity to tranexamic acid

• pregnant woman

• fertile female who don't use contraception