Effect of Transcranial Direct Current Stimulation (tDCS) and Probiotic Supplementation in Overweight Adults

• Status: Recruiting
• Trial end date: 2024-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the current study is to investigate and compare the effectiveness of probiotic supplementation and tDCS stimulation on risky decision-making related to food choices in overweight people. Considering the relatively established communication and interaction between the gut-brain-microbiome axis, the investigators expect that transcranial direct current stimulation and probiotic supplementation can both improve decision-making (decrease risky and impulsive decisions) and increase self-control in overweight people.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Tehran
• Collaborators: Tabriz University; University of Messina

Criteria

Inclusion Criteria:

• BMI over 25

• Higher than normal fat level

Exclusion Criteria:

• Pregnancy

• Breastfeeding

• Smoking more than 10 cigarettes a day

• Excessive consumption of alcohol

• Suffering from chronic cardiovascular and kidney diseases

• Chronic digestive diseases such as celiac disease,

• Chronic inflammatory bowel diseases such as colitis, intestinal surgery, cancer, etc.

• Suffering from acute and chronic diarrhea in the last one month

• Taking antibiotics in two months before the start of the study,

• Continuous use of prebiotic and probiotic products and drugs in one month before the start of the intervention

• Frequent use of antibiotics during the last month before the start of the intervention

• Taking weight loss medications and following a special slimming diet in the last 3 months before the intervention.

• History of epilepsy and seizures, stroke,

• Use of pacemaker

• Presence of metal implanted in the scalp or brain,

• Presence of skin lesions at the tDCS stimulation site, and history of head injury or brain surgery.

• Brain disorders and long-term and chronic use of neuropsychiatric drugs.