Effect of Ultimaster Stents Treated to the Most Dilated Coronary Vessels
Status:
Not yet recruiting
Trial end date:
2024-07-31
Target enrollment:
Participant gender:
Summary
In patients with vasospasm or with negative remodeling, various vasodilator drugs used during
coronary angiography can dilate the diameter of the reference vessel to measure the exact
vessel size. In particular, nitrates are well known to induce pharmacological vasodilatory
effects through vascular smooth muscle relaxation In actual clinical practice, it has been
reported that when oral or spray-type nitrate preparations are administered to coronary
artery stenosis lesions, the diameter of the reference vessel expands by about 10% compared
to the existing vessel diameter. This may enable larger stenting in coronary artery stenosis
lesions. Although many patients with vascular stenosis are accompanied by vasospasm and voice
remodeling, in actual clinical practice, administration of vasodilators is only used in a
small number of patients at the discretion of the surgeon. Nitrate vasodilators administered
during coronary angiography are low-dose and short-acting drugs, and although a small number
of patients may experience side effects such as short-term lowering of blood pressure, no
serious side effects are reported .
On this background, this study is to evaluate whether there is a difference in the diameter
of the Ultimaster® stent treated with the conventional method compared to the maximally
dilated coronary artery, and to evaluate the stability and effectiveness after the procedure.