Effect of Vasopressin, Steroid, and Epinephrine Treatment in Patients With Out-of-hospital Cardiac Arrest

• Status: Unknown status
• Trial end date: 2020-08-09
• Target enrollment: 0
• Participant gender: All

Summary

Steroid use could be considered for patients with weaker adrenal function among those with post-cardiac arrest (CA) return of spontaneous circulation (ROSC), according to the former study. This finding is consistent with the medical background of this present study. This study will be the first to investigate these additional drugs of injection and associated prognosis in cardiac arrest (CA) patients outside the hospital, providing significant basic data.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Korea University Guro Hospital
• Treatments: Arginine Vasopressin; Epinephrine; Epinephryl borate; Methylprednisolone; Methylprednisolone acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate; Racepinephrine; Vasopressins

Criteria

Inclusion Criteria:

• The group of patients who participated in the study included adults aged at least 19 years among the atraumatic CA outpatients who came to the ER and received CPR.

Exclusion Criteria:

• Pregnant women and young children aged <18 years;

• Patients with underlying disease cases without the possibility of resuscitation (e.g., terminal cancer);

• Patients with do-not-resuscitate (DNR) status;

• Death by excessive bleeding (e.g., abdominal main artery rupture);

• Patients who have experienced in-hospital CA;

• Patients previously treated with steroid, anti-cancer medicine, or immunosuppression treatment before CA;

• Patients already been registered with other studies; or

• Patients from whom informed consent cannot be obtained