Effect of Vitamin D Replacement During Winter Months in Patients With Hypertension

• Status: Completed
• Trial end date: 2011-04-01
• Target enrollment: 0
• Participant gender: All

Summary

High blood pressure is related to increased risk of cardiovascular disease and death, and accounts for approximately 8 mill deaths worldwide each year. Blood pressure exhibits a seasonal variation with a tendency to increase during winter months. Vitamin D deficiency is more common during months where UVB radiation from the sun is absent, and vitamin D has been associated with high blood pressure. This study will evaluate the effect of vitamin D replacement during winter months on blood pressure and vasoactive hormones in patients with high blood pressure.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Regional Hospital Holstebro
• Treatments: Cholecalciferol; Vitamin D

Criteria

Inclusion Criteria:

• Well-regulated arterial hypertension

• Office blood pressure > 120/70 mmHg

Exclusion Criteria:

• Pregnancy or nursing

• Cancer

• Alcohol abuse

• Continuous glucocorticoid or NSAID treatment

• 24-hour blood pressure > 150/95 mmHg

• Hypercalcemia