Effect of Volume of Local Anesthetic for Adductor Canal Block on Quadriceps Muscle Function: A Dose Finding Study

• Status: Completed
• Trial end date: 2015-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Adductor canal block is commonly offered to provide pain relief following knee surgery with the hope that they cause less leg weakness than traditionally performed femoral nerve block. Infrequently, adductor canal blocks also result in leg weakness thereby potentially limiting the advantages of the technique. Investigators want to find out the effective dose for a 30% response (volume of local anesthetic which would result in clinically significant weakness of the leg)

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Lawson Health Research Institute
• Treatments: Anesthetics; Anesthetics, Local; Ropivacaine

Criteria

Inclusion Criteria:

• Male and females

• Age 16-60 years

• Scheduled surgery

• Knee arthroscopy

• ASA Class I - III

Exclusion Criteria:

• Ipsi- or contralateral leg weakness

• Preoperative neurological deficits

• Narcotic dependent (opioid intake more than 3 months)

• Chronic pain conditions

• Significant cardiac and respiratory disease

• Coexisting hematological disorder or with deranged coagulation parameters

• Pre-existing major organ dysfunction such as hepatic and renal failure.

• Psychiatric illnesses

• Emergency surgery

• Lack of informed consent

• Allergy to any of the drugs used in the study