Effect of Zydena (Udenafil) on Cerebral Blood Flow and Peripheral Blood Viscosity

• Status: Unknown status
• Trial end date: 2012-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether Zydena (Udenafil) has effect on cerebral blood flow and peripheral blood viscosity in normal and subcortical vascular cognitive impairment subjects.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Samsung Medical Center
• Collaborator: Dong-A Pharmaceutical Co., Ltd.
• Treatments: Udenafil

Criteria

Inclusion Criteria:

for Normal control group

• Normal cognition by detailed neuropsychological tests

• Brain MRI scan with no or minimal white matter hyperintensities

for Subcortical vascular mild cognitive impairment (svMCI)

• Clinical diagnosis of svMCI

• Brain MRI scan with severe white matter hyperintensities

Exclusion Criteria:

• Contraindications to phosphodiesterase type 5 (Zydena, Udenafil)