Overview

Effect of a Perioperative Oral Nutritional Supplementation on Patients Undergoing Hepatic Surgery for Liver Cancer

Status:
Terminated
Trial end date:
2008-09-01
Target enrollment:
Participant gender:
Summary
Cirrhotic patients undergoing hepatic resection have a mortality rate near 10%, and 30 to 70% of them develop severe complications. These failures are mainly due to hepatic insufficiency. Studies have already shown benefits of oral nutritional supplements in ORL, digestive, and cardiac surgery. We aimed to ascertain whether this nutritional, immune-enhancing supplementation, administered 7 days before and 3 days after surgery, could improve liver function and postoperative host defences in patients with liver cancer resection.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Rennes University Hospital
Collaborators:
Ministry of Health, France
Novartis