Effect of no Drainage Tube on Blood Loss and Recovery After High Tibial Osteotomy

• Status: Completed
• Trial end date: 2019-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study was to evaluate the safety and efficacy of topical combined with intravenous tranexamic acid for high tibial osteotomy without placement of a drainage tube The clinical scores of patients and their possible risks were tracked. The investigators hypothesized that a combination of tranexamic acid and no drainage tube could reduce blood loss and facilitate early recovery. The implementation of the study will provide a new perioperative blood loss control program for High Tibial Osteotomy, reduce the cost of hospitalization, promote patients to get out of bed early, reduce the number of days in hospital.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Qilu Hospital of Shandong University
• Treatments: Pharmaceutical Solutions; Tranexamic Acid

Criteria

Inclusion Criteria:

1. Simple knee medial compartment osteoarthritis High tibial osteotomy.

2. With varus deformity, medial proximal tibia angle <85°

3. Unilateral High tibial osteotomy

4. informed consent: Participants must be able to understand and voluntarily sign a written informed consent and follow the research protocol and interview process

Exclusion Criteria:

1. patients who underwent other knee surgery within 6 months

2. Preoperative combined anemia (Hb<100g/l)

3. Patients with severe cardiovascular, hepatic, renal and hematopoietic diseases

4. Patient with preoperative coagulation abnormalities 5. Patients with allergies and patients allergic to TXA.