Effect on Fenoterol Metered Dose Inhaler on the Beta-receptor Population on Lymphocytes in Patients With Bronchial Asthma

• Status: Terminated
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study was to compare the effect of fenoterol metered dose inhaler with disodium cromoglycate (DSCG) metered dose inhaler on the lymphocyte β2-receptor population as well as on the clinical findings in patients with bronchial asthma over a two-week period of treatment.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Boehringer Ingelheim
• Treatments: Fenoterol

Criteria

Inclusion Criteria:

• sex: male and female

• age: 18 years or over

• bronchial asthma, diagnosis confirmed by history and positive inhalation challenge test (unspecific challenge with carbachol, PD100SRaw))

• severity of asthma mild to moderate or asthmatic in symptom-free intervals

• Raw ≤ 5 cm H2O/l/s

• no antiasthmatic treatment in the week (steroid therapy: two weeks) before the start of the study

Exclusion Criteria:

• clinically significant, concomitant haematological, cardiac, renal, hepatic or metabolic diseases

• intercurrent diseases, e.g. severe respiratory infections

• patients who cannot do without the following preparations during the 5-week trial:

• inhaled/oral steroids

• theophylline

• antihistamine, antiallergic drugs

• inhaled/oral sympathomimetics

• anticholinergics