Effect on Tear Functions of Pretarsal and Preseptal Techniques of Botulinum Toxin Type A Injection in Hemifacial Spasm

• Status: Unknown status
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether pretarsal and preseptal techniques of Botulinum toxin type A injection have any effect on tear functions.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Khon Kaen University
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; incobotulinumtoxinA; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• patient diagnosed with hemifacial spasm

Exclusion Criteria:

• previous history of botulinum toxin treatment for hemifacial spasm

• ocular surface disorders

• tear disorders

• evidence of infection at or around eyelids

• pregnant woman

• other neurologic disease, i.e. OMG

• coagulopathy or treatment with thrombolytic agent

• treatment with aminoglycosides, chloroquine, hydroxychloroquine