Effectiveness Study of Different Local Anesthetic Mixtures
Status:
Completed
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
Purpose and Background The purpose of this research study is to investigate the benefits of
mixing lidocaine and bupivacaine for numbing the skin. Lidocaine and bupivacaine are two
commonly used medications to numb the skin for minor procedures. Lidocaine has a faster
onset. Bupivacaine has a longer duration. They are often combined with epinephrine to
increase the length of action. These medications are used to control pain at the time of the
operation and to decrease discomfort immediately afterward. Participating in the study
involves injection of local anesthetic containing lidocaine, bupivacaine, and lidocaine and
bupivacain with epinephrine at 4 sites on the forearm. Your participation will potentially
improve the administration of these medications in persons undergoing a variety of
procedures. You will be one of approximately 25 healthy volunteer subjects in this research
study.