Effectiveness and Safety of Breeded Leech for Symptomatic Primary Arthrosis of the First Carpometacarpal Joint

• Status: Terminated
• Trial end date: 2018-12-01
• Target enrollment: 0
• Participant gender: All

Summary

In this trial the investigators want to prove the efficacy and safety of a one-time topical leech application at patients with symptomatic primary arthrosis of the first carpometacarpal joint in comparison to the standard therapy with topical diclofenac.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Charite University, Berlin, Germany
• Treatments: Diclofenac

Criteria

Inclusion Criteria:

• Male and female patients aged 35 to 85 years

• Pain intensity in the region of the thumb base in pain phases ≥ 40 mm on the VAS of 0 to 100 mm (relative to the last 24 hours)

• Complaints for at least 3 months

• X-ray Stadium Eaton I-IV at least once secured

Exclusion Criteria:

• Anticoagulation (Marcumar, Heparin)

• Haemophilia, V. Willebrandt Jürgens syndrome, thrombocytopathy and other blood anomalies

• Combination therapy of ASA and thienopyridines

• Pain medication with opioid analgesics

• Systemic medication with corticoids or immunosuppressants

• Intraarterticular injections or RSO within the last 3 months

• Past or planned surgery on the affected joint in the next 2 months

• Pregnancy, lactation

• Insulin-dependent type I diabetes mellitus

• Acute psychotic disorders

• Severe comorbidity