Effectiveness and Safety of Chinese Medicine to Treat Hand, Foot, and Mouth Disease

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study is aimed to evaluate the effectiveness and safety of Xiyanping injection,a traditional Chinese medicine (TCM), in the treatment of severe type of hand, foot, and mouth disease (HFMD).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jiangxi Qingfeng Pharmaceutical Co. Ltd.
• Collaborators: Beijing University of Chinese Medicine; Beijing YouAn Hospital; China Academy of Chinese Medical Sciences; The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
• Treatments: Antibodies; Immunoglobulins; Immunoglobulins, Intravenous; Mannitol; Methylprednisolone; Methylprednisolone acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• Clinical diagnosis of severe hand-foot-mouth disease patients according to Hand-Foot-Mouth Disease Treatment Guidelines 2010 issued by China's Ministry of Health; More than 1/3 patients should be diagnosed by etiological examination.

• Less than 24 hours of occurrence of fever and/or occurrence of tetter or herpes.

• Age of 1-13 years.

• Patients or their guardians agree to participate in this study and signed the informed consent form.

Exclusion Criteria:

• Complicated with other diseases such as neurogenic pulmonary edema, cardiopulmonary failure.

• Complicated with other serious primary diseases in organ such as congenital heart disease, chronic hepatitis, nephritis and blood diseases, etc.

• With history of allergies on traditional Chinese medicine.

• Patients who using glucocorticoids for based diseases.

• Patients who having history of hemolysis.

• Patients or their guardians suffering from Psychiatric diseases.

• Attending other clinical studies on HFMD after diagnosed.