Effectiveness of Antibiotics Versus Placebo to Treat Antenatal Hydronephrosis
Status:
Active, not recruiting
Trial end date:
2021-09-01
Target enrollment:
Participant gender:
Summary
This study focuses on the relationship between prophylaxis antibiotics and frequency of
urinary tract infection in children diagnosed with antenatal hydronephrosis. Hydronephrosis
is the most common fetal abnormality occurring in 1-5% of all pregnancies. Currently, with
the widespread accessibility of antenatal ultrasound across cities in Ontario, the detection
of hydronephrosis has become even more common. As a result, thousands of infants with
hydronephrosis have been seen and managed by pediatricians, pediatric nephrologists,
pediatric urologists, and family physicians. The investigators need to determine if
antibiotic prophylaxis is effective in reducing the number of urinary tract infections in
this population.
Phase:
N/A
Details
Lead Sponsor:
McMaster University
Collaborators:
Hamilton Health Sciences Corporation McMaster Surgical Associates The Physicians' Services Incorporated Foundation