Effectiveness of Bupropion in Treating Marijuana Dependent Individuals

• Status: Completed
• Trial end date: 2006-05-01
• Target enrollment: 0
• Participant gender: All

Summary

A definable and significant withdrawal syndrome occurs upon cessation of chronic, heavy marijuana use. Bupropion (Zyban) is a medication currently used to treat withdrawal symptoms associated with tobacco use. The purpose of this study is to determine if bupropion will help individuals stop using marijuana.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Bupropion

Criteria

Inclusion Criteria:

• Current marijuana use and dependence

• Marijuana use of at least 5 times in the past 7 days or more than 25 times per month for the 3 years prior to enrollment

• Unsuccessful in a previous attempt to quit marijuana

Exclusion Criteria:

• Axis I disorder

• Any drug abuse or dependence other than marijuana

• Currently taking antipsychotic or antidepressant medication

• Heavy alcohol drinker (more than 20 drinks per week)

• Current nicotine dependence

• History of a seizure disorder

• Current or prior eating disorder (e.g., bulimia or anorexia nervosa)

• Heavy caffeine use (more than 300 mg per day)

• Life threatening or unstable medical illness

• Pregnant