Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Children
Status:
Recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
Generalized status epilepticus is a common pediatric neurological emergency with significant
mortality and morbidity. Benzodiazepines remain the first anticonvulsive line but
benzo-diazepines don't control seizures in about 30% of cases. GCSE may be more rapidly
stopped and controlled through combining another drug with benzodiazepines such as
Levetiracetam, acting by different pathways. This study aims to evaluate the effectiveness of
combined levetiracetam and midazolam in treatment of generalized convulsive status
epilepticus in children.