Effectiveness of Diclofenac and Its Association to Codeine After Lower Third Molar Extraction.

• Status: Completed
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

It will be evaluated the clinical efficacy of Diclofenac 50mg (NSAID) compared to its association with Codeine 50mg (opioid) administered in 50 patients requiring extraction of two third molars. After assessing the research parameters, a comparative data analysis, along with the proper application of statistical tests, will provide the basis for an evaluation of both efficiency medications used.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Sao Paulo
• Collaborator: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
• Treatments: Anti-Inflammatory Agents, Non-Steroidal; Codeine; Diclofenac

Criteria

Inclusion Criteria:

• Impacted lower third molar

• not in use of NSAID or opioids in the last one month

Exclusion Criteria:

• Local anesthetics allergy,

• History of gastrointestinal bleeding or ulcers,

• Kidney disease,

• Asthma,

• Allergy or sensitivity to aspirin or any other NSAID or opioids,

• Pregnant or nursing woman,

• Patients using antidepressant, diuretic or aspirin,

• Patients under treatment to quit drugs