Effectiveness of Minocycline-Containing Bismuth Quadruple Therapy for Helicobacter Pylori Eradication
Status:
Not yet recruiting
Trial end date:
2021-07-05
Target enrollment:
Participant gender:
Summary
Although,bismuth-containing quadruple therapy has been highly recommended as first-line
treatment regimen for H.pylori infection,it also has its problems and limitations in
China.The primary resistance rates of metronidazole,clarithromycin and levofloxacin are all
high in China.Besides that,tetracycline cannot be obtained and its complicated administration
(four times daily) easily reduce patient compliance. In this study, we proposed to evaluate
the eradication rate, safety, and compliance of a minocycline-based bismuth quadruple
regimen.
Phase:
N/A
Details
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University