Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis
Status:
Completed
Trial end date:
2020-03-15
Target enrollment:
Participant gender:
Summary
Chronic rhinosinusitis (CRS) affects up to 12.5% of the US population and has a significant
disease burden. The recommended medical management of CRS includes large-volume, low-pressure
saline lavage, systemic antibiotics, and intranasal corticosteroids (INCS). While the
efficacy and safety of INCS are well-established for the long-term management of CRS,
penetration of INCS beyond the nasal vestibule and into the paranasal sinuses is limited. The
aim of this study is to evaluate the effectiveness of mometasone furoate large-volume,
low-pressure nasal irrigation for surgery-naive CRS patients.