Effectiveness of Multicomponent Lipid Emulsion in Preterm Infants Requiring Parenteral Nutrition

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the effects of a multicomponent lipid emulsion containing 30% soybean oil, 30% medium-chain triglycerides, 25% olive oil, and 15% fish oil with a conventional pure soybean oil lipid emulsion on the incidence of neonatal cholestasis, infant growth, infant morbidity and the biochemical assessment of liver enzymes.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Thammasat University
• Treatments: Soybean oil, phospholipid emulsion

Criteria

Inclusion Criteria:

• Inborn infants with a gestational age of less than 30 weeks

• Who required parenteral nutrition for at least 7 days

Exclusion Criteria:

• Evidence of congenital infection

• Perinatal asphyxia

• Congenital anomalies

• Severe IVH

• Thrombocytopenia

• Shock or circulation failure

• Renal or hepatic disorders.