Overview

Effectiveness of N-acetyl Cysteine, Acetyl L- Carnitine and Medicated Paraffin Oil in Aluminium Phosphide Poisoning

Status:
Not yet recruiting

Trial end date:
2021-12-01

Target enrollment:
0

Participant gender:
All

Summary

Aluminium Phosphide is a pesticide used in developing countries to prevent rodents and pests from spoiling the harvested grains. it is presented as tablets which can be administered accidently to humans or for committing suicide. this pesticide is fatal even in small concentration as mortality rate can reach 75- 100% of cases. in this study researchers tried to add some supplements to the routine treatment to improve and decrease the fatality rate.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Cairo University

Collaborator:

Ain Shams University hospitals

Treatments:

Acetylcarnitine
Acetylcysteine
Mineral Oil
N-monoacetylcystine
Ondansetron

Criteria

Inclusion Criteria:

- All adult patients with history of acute intoxication with AlP presented to the Poison
Control Center of Ain-Shams University hospitals during the period of the study

Exclusion Criteria:

1. Patients less than 18

2. Patients presented with delay time exceeding 12 hours after acute intoxication.

3. Patients with history of cardiac, renal or hepatic diseases.

4. Patients who show hypersensitivity to NAC, ALCAR or paraffin oil.