Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity

• Status: Completed
• Trial end date: 2017-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare the efficacy of dentine hypersensitivity reduction using in office paste formula containing nanoHydroxyapatite with the commercially available fluoride (duraphat) and a placebo in treating hypersensitivity in a single visit.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Riyadh Colleges of Dentistry and Pharmacy
• Treatments: Fluorides; Fluorides, Topical; Glycerol; Listerine; Sodium Fluoride

Criteria

Inclusion Criteria:

• Hypersensitive areas on facial surfaces of the teeth (incisors, canines, premolars, and first molars with exposed cervical dentin) with at least two teeth scoring "pain (scale stimuli test, scores 2 and 3)" during application of stimulus (airblast and tactile sensitivity test)

• Good periodontal health (no probing depth > 4 mm) with no other conditions that might explain their apparent dentin hypersensitivity

• Good overall physical health

• Age between 18 and 45 years

• Provision of written informed consent

• Patient willing to participate in the study

Exclusion Criteria:

• Chipped teeth

• Defective restorations

• Fractured undisplaced canines

• Deep dental caries

• Deep periodontal pockets

• Orthodontic appliances

• Dentures or fixed dental prostheses that would interfere with the evaluation of hypersensitivity

• Periodontal surgery within the previous 6 months

• Ongoing treatment with antibiotics and/or anti- inflammatory drugs past 3 months

• Ongoing treatment for tooth hypersensitivity

• Pregnancy or lactation

• Smokers