Effectiveness of Nefazodone and Bupropion in Treating Marijuana Dependent Individuals
Status:
Completed
Trial end date:
2004-09-01
Target enrollment:
Participant gender:
Summary
Recent research has identified the following withdrawal symptoms to be associated with
abruptly stopping marijuana use: anxiety, irritability, bodily aches and pains, and
difficulty sleeping. These symptoms resemble those of both depression and nicotine
withdrawal, suggesting that a similar treatment drug may be useful. This study will evaluate
the effectiveness of two antidepressant drugs, bupropion and nefazodone, in reducing
withdrawal symptoms in marijuana dependent individuals.