Effectiveness of Recombinant Human Growth Hormone Therapy for Children With PMS

• Status: Completed
• Trial end date: 2021-06-08
• Target enrollment: 0
• Participant gender: All

Summary

In summary, this piot study with 6 participants shown that recombinant human growth hormone (rhGH) has a positive effect on the treatment with PMS. In addition, This study indicated that rhGH can improve PMS symptoms via increase the level of serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein 3 (IGFBP-3). RhGH may be low cost, more accessible, alternative treatment for PMS.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Affiliated Hospital of Jiangnan University
• Treatments: Hormones

Criteria

Inclusion Criteria:

• Patients diagnosed with PMS aged from 1years to 5 years

Exclusion Criteria:

• active or suspected tumour, intracranial hypertension, chronic kidney disease, acute proliferative or severe nonproliferative diabetic retinopathy, allergy to rhGH or severe comorbidity