Effectiveness of Sugammadex in LMS Surgery

• Status: Unknown status
• Trial end date: 2016-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is comparing of rocuronium-sugammadex and succinylcholine during LMS surgery that is characterized by short operation time, required intense paralysis and ambulatory setting, has not been investigated.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Korea University Anam Hospital
• Treatments: Cisatracurium; Neostigmine; Pyridostigmine Bromide; Rocuronium; Succinylcholine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologist[ASA] class 1-3

• scheduled Laser microlaryngeal surgery under general anesthesia

• written informed consent

Exclusion Criteria:

• suspected difficult tracheal intubation

• disorder affecting neuromuscular blockade

• known or suspected significant renal dysfunction

• known or suspected severe hepatic dysfunction

• history of malignant hyperthermia

• allergy of opioids, neuromuscular blocking drugs or other medications used during general anesthesia

• contraindication to pyridostigmine and/or atropine

• pregnancy

• breast feeding

• body mass index > 27kg/m2