Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint
Status:
Unknown status
Trial end date:
2020-09-01
Target enrollment:
Participant gender:
Summary
This prospective study will be quantitatively analyzing the effectiveness of
platelet-rich-plasma (PRP) injections into the sacroiliac (SI) joint in relieving
sacroiliitis and low back pain originating from the SI joint. The effectiveness of PRP
injections on joint pain has been well studied in the knee and shoulder. PRP injections are
performed on the SI joint commonly, but there is little research documenting their
effectiveness when compared to other interventions. This study will be a small pilot study to
aid in closing this knowledge gap. Additionally, these injections will be performed under
ultrasound guidance. Ultrasound has been proven to be of equal reliability to fluoroscopy and
has the advantage of shorter time to administer and no radiation. There will be one arm to
this study. The data collected will be compared to existing studies on corticosteroid SI
joint injection. The experimental arm consists of the PRP injection. The PRP will be injected
into the joint using the exact same technique via physical exam, special tests, and
ultrasound guidance as performed in our previous studies. The outcomes will be measured with
the Numeric Rating Scale for Pain (NRS) and the Oswestry Disability Index (ODI) prior to the
injection, immediately post-injection, 2 weeks, 4 weeks, 3 months, 6 months, 9 months, and 1
year post-injection. The investigators hypothesis is, "Platelet-Rich Plasma Injections in the
Sacroiliac Joint using ultrasonography in conjunction with physical examination and Point of
Maximal Tenderness will produce statistically significant pain relief for more than 3 months
as measured by the Numeric Rating Scale for Pain (NRS) and Oswestry Disability Index (ODI)."