Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1

• Status: Completed
• Trial end date: 2004-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Currently one in five high school students smokes. Smoking can harm adolescents well before they reach adulthood by causing a number of immediate, sometimes irreversible, health risks and problems. This study will compare the effectiveness of treatment with bupropion, a nicotine patch, or nicotine gum in supporting the reduction of smoking in adolescent smokers.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Folic Acid; Nicotine; Vitamin B Complex

Criteria

Inclusion Criteria:

• At least 6 months of daily cigarette smoking

• No use of other tobacco products

• Motivated to reduce or quit smoking

• Not currently using medications to quit smoking

• Agree to use an effective form of contraception throughout the study

Exclusion Criteria:

• People for whom use of nicotine replacement therapy or bupropion is medically inadvisable

• History of alcohol or drug abuse within 6 months of enrollment

• History of emotional problems (as assessed by the Adolescent Symptoms Inventory) within 6 months prior to enrollment

• Currently on an unstable dose of psychoactive medications

• Currently taking medications that may react with one of the treatment medications

• Pregnant