Effectiveness of Vitamin B in Reducing Temporomandibular Joint Disorder Pain

• Status: Completed
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine effectiveness of vitamin B in reducing temporomandibular joint disorder (TMD) pain. Patients will be randomised to receive the study drug or placebo. The study drug we are using is a combination of vitamin B1(thiamine mononitrate)-242.5mg; vitamin B6(pyridoxineHCl)-250mg, and vitamin B12(cyanocobalamin)-1mg. We will assess patient's pain level, range of jaw movement and record any side effects from using this medication.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Hong Kong
• Treatments: Vitamin B Complex; Vitamins

Criteria

Inclusion Criteria:

• minimum age of 18

• temporomandibular joint disorder with pain

• chronic condition- symptoms lasting more than 3 months with at least 2 episodes of pain in last 1 month

• language competence- in Cantonese or English

• all ethnicity

Exclusion Criteria:

• ankylosis of the joint

• limited mental capacity

• pregnancy and lactating mothers

• inability to take medications (NSAIDS-Ibuprofen or Vitamin B)

• undergoing concurrent pharmacotherapy with anti inflammatory or muscle relaxant medications

• poor general health

• history of TMJ trauma or TMJ surgery

• subjects taking Vitamin B for other uses