Effectiveness of Vitamin D in Primary Dysmenorrhoea

• Status: Completed
• Trial end date: 2013-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

Vitamin D in the treatment of primary dysmenorrhoea. Design:Randomised controlled trial. Setting:In a university hospital. Population: 142 women aged 16-35 years. Methods: Patients were treated with 667 unit of vitamin D once a day, 200 unit of vitamin E once a day or 400 mg ibuprofen twice a day,2 days before the date of menstruation and continued through the first 3 days, for 2 months. Main outcome measures: Pain score. Results: Mean VAS of vitamin D group was 4,91, was 6,54 in the vitamin E group and was 4,02 in the ibuprofen group Conclusion:Vitamin D and vitamin E are effective in relieving the pain,but the effect of vitamin D are more prominent

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Bezmialem Vakif University
• Collaborators: Gulsah Ilhan; Mucize Ozdemir; Osman Sevket; Seda Ates; Yildirim, Zeynep Baysal, M.D.
• Treatments: alpha-Tocopherol; Ergocalciferols; Ibuprofen; Tocopherols; Tocotrienols; Vitamin D; Vitamin E; Vitamins

Criteria

Inclusion Criteria:

1. Women had regular menstrual cycles lasted 21 to 35 days, with menstruation lasting 3 to 7 days;

2. Women had to be in good health and taking no medications including calcium, magnesium, vitamin D and oral contraceptives.

3. Women had not a previous history of gynaecological disease, and a normal pelvic examination were eligible.

Exclusion Criteria:

1) Previous and current use of intrauterine contraceptive devices within the 6 months to enrollment was not permitted