Effectiveness of an Internet-based Intervention for the Treatment of Depression

• Status: Completed
• Trial end date: 2019-11-13
• Target enrollment: 0
• Participant gender: All

Summary

Depression is a highly prevalent disorder in Chile, generating important personal and social costs. This study aims to evaluate the effectiveness of the internet-based program ASCENSO as an adjunct intervention for the treatment of depression. ASCENSO provides information to promote patients' self-care, it monitors reported depression symptoms providing automatized feedback and provides the possibility of booking a counseling session via chat or by phone. To evaluate the effectiveness of ASCENSO, an open, evaluator-blind, prospective, parallel-group (one intervention group and one active control group) randomized controlled trial will be implemented in one mental health center in Santiago of Chile. The sample will be composed of adults initiating treatment for depression, and who have internet access. Participants will be randomly assigned to one of the two study arms. Randomization will be stratified by the number of patients´ previous episodes (dichotomized into none, 1 or more), following a permuted block randomization procedure. Patients in the experimental group (n=100) will receive the usual treatment plus access to the ASCENSO program. The control group (n=100) will only receive the usual treatment. At recruitment, months 6 and 9, patients' self-reported depression symptoms and quality of life will be assessed. Additionally, adherence to treatment in terms of patients' attendance to medical controls and psychotherapy sessions will be registered for both research groups.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto Milenio para Investigación en Depresión y Personalidad
• Collaborators: Fondo Nacional de Investigación y Desarrollo en Salud, Chile; National Fund for Research and Development in Health, Chile; Psicomedica Clinical & Research Group, Chile; University Hospital Heidelberg
• Treatments: Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents

Criteria

Inclusion Criteria:

• Clinical diagnosis of major depression disorder

• Internet access

Exclusion Criteria:

• previous suicide attempt

• hospitalization for a previous depressive episode

• a history of psychotic symptoms

• bipolar disorder

• organic brain disorders

• any serious disorders related to substance abuse or dependence

• antisocial personality disorder

• a serious medical condition or severe cognitive impairment

• lack of knowledge of the Spanish language

• illiteracy

• refusal or revocation of patient consent.

Patients will be evaluated using the MINI International Neuropsychiatric interview, Spanish for Chile Translation Version 6.0.0.