Effects Of Oral Alfacalcidol On Maturation Of Dendritic Cells In Graves' Disease Patients
Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
Maturity level of dendritic cells (DC) plays a pivotal role in initiating and regulating
autoimmunity. In Graves' disease (GD), DCs have more active immune responses than those in
healthy subjects. Our previous study demonstrated immunoregulatory effects of in vitro
1,25-D3 on maturation of DC in GD patients. This study aims to evaluate the effect of oral
1α-D3 on DC maturation in GD patients.