Effects Of The Drug Ketoconazole On How The Body Handles The Drug SB773812

• Status: Completed
• Trial end date: 2007-10-10
• Target enrollment: 0
• Participant gender: Male

Summary

The purposes of this study are to determine if there is a difference in how SB-773812 is distributed through the bloodstream before and after multiple doses of ketoconazole have been given and to determine if there is a difference in how safe and well tolerated SB-773812 is when given on its own and given with ketoconazole.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: GlaxoSmithKline
• Treatments: Ketoconazole

Criteria

Inclusion criteria:

• Healthy

• Body Weight >/=50kg and BMI 18.5-29.9 kg/m2 inclusive

• Normal 12-lead ECG, physical examination and lab screen

Exclusion criteria:

• A history of psychiatric illness,

• A history or presence gastro-intestinal,

• A hepatic or renal disease or orthostatic hypotension.