Effects Vitamin D Suppletion on Postprandial Leukocyte Activation

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Administration of vitamin D will have a beneficial effect on postprandial leukocyte activation, oxidative stress and arterial stiffness in vitamin D deficient females. High doses of vitamin D may have a more pronounced effect than low doses.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sint Franciscus Gasthuis
• Treatments: Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Age of 18 years or older;

• Pre-menopausal;

• BMI ≥25.0 kg/m2;

• Vitamin D deficiency, defined by a 25-hydroxyvitamin D level of <30ng/ml;

• Use of oral contraceptives.

Exclusion Criteria:

• The use of any kind of medication except oral contraceptives;

• Smoking;

• Pregnancy;

• Participation in a clinical study less than 6 months before inclusion;

• The use of (multi)vitamin supplements.