Effects and Safety of Infusion of Low-Doses of Methylprednisolone in Early ALI and ARDS in Children
Status:
Withdrawn
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the effects of prolonged low-dose
methylprednisolone infusion on pulmonary function (LIS and ventilation-free days), extra
pulmonary organ function (PMODS score), inflammatory markers - RCP (Reactive C Protein), IL6
(Interleukine 6), TNFα (Tumor Necrosis Factor), IL8 (Interleukine 8), IL10 (Interleukine 10)
and length of Pediatric Intensive Care Unit (PICU) stay in early ALI/ARDS in children.
Phase:
Phase 2
Details
Lead Sponsor:
Universidade Federal do Rio de Janeiro
Collaborators:
Instituto D'Or de Pesquisa Instituto de Puericultura e Pediatria Martagão Gesteira - IPPMG/UFRJ Rio de Janeiro State Research Supporting Foundation (FAPERJ)