Effects of 2 Different Duration of Albendazole Therapy in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT

• Status: Completed
• Trial end date: 2015-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Comparing the effect of two different duration of same drug albendazole in patients with Neurocysticercosis less than or equal to 5 lesions on CT head at the end of 6 months.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: All India Institute of Medical Sciences, New Delhi
• Treatments: Albendazole

Criteria

Inclusion Criteria:

• Age 2-18 years.

• Number of parenchymal lesions: upto 5*

• Stages of cysticerci at which albendazole treatment is effective

• Vesicular stage

• Colloid vesicular stage

• Granular nodular stage

Exclusion Criteria:

• Cysticercotic encephalitis

• Calcified cyst

• Hydrocephalus

• Intraventricular cyst

• Subarachnoid cyst

• Ophthalmic Cysticercosis

• No of cysts >5

• Known allergy to benzimidazole class of compound which includes anaphylaxis, hypotension, severe skin reactions .

• Features of raised ICT (papilloedema, hyperventilation, hypertension, tonic posturing, B/L 6th nerve palsy, features of midline shift on CT/MRI)

• Critically sick (respiratory failure, cardiovascular instability)

• Already received albendazole or praziquantel or steroid therapy