Overview

Effects of Adding Hypertonic Saline Solutions and/or Etilefrine to Standard Diuretics Therapy in Hepatic Ascites

Status:
Completed
Trial end date:
2020-04-30
Target enrollment:
Participant gender:
Summary
This work aimed to evaluate and compare the impact of adding hypertonic saline solution (HSS) infusion and/or etilefrine to oral diuretics therapy on clinical outcomes, renal and systemic hemodynamics, metabolic and inflammatory pathways by estimating the changes in selected biological markers in cirrhotic patients with ascites. Also, the trial aims to assess the safety and tolerability of such treatment regimens.
Phase:
Phase 2
Details
Lead Sponsor:
Hala Abd EL-Tawab Ibrahim Radwan
Treatments:
Diuretics
Etilefrine
Furosemide
Pharmaceutical Solutions
Spironolactone