Effects of Aliskiren in Elderly Hypertensive Chronic Kidney Disease (CKD) Patients

• Status: Completed
• Trial end date: 2012-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether aliskiren is effective in the treatment of blood pressure, hear function, renal function in elderly hypertensive chronic kidney disease (CKD) patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jichi Medical University

Criteria

Inclusion Criteria:

• Clinical diagnosis of Chronic kidney disease

• Clinical diagnosis of Hypertension (Blood pressure >=140/90mmHg)

• Elderly people(>=65 years old)

Exclusion Criteria:

• The patients who are already taking aliskiren

• The patients who are receiving hemodialysis or peritoneal dialysis

• The patients who are taking cyclosporin

• The patients who have hyperkalemia(>=5.5mEq/ml)

• Severe heart failure (>=NYHA class III)

• Insulin dependent diabetic mellitus or poor controlled insulin independent diabetic mellitus (>=HbA1c 9.0&)

• Severe liver dysfunction (five folds increased AST or ALT than standard values)