Overview

Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function

Status:
Recruiting
Trial end date:
2022-03-31
Target enrollment:
Participant gender:
Summary
Multicentre, multinational, prospective randomised, open-label, 3 sequence crossover phase III b clinical trial with blinded endpoint assessment (PROBE-design) - in 75 patients with sporadic small vessel diseases (SVDs) and - in 30 patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
Phase:
Phase 3
Details
Lead Sponsor:
Ludwig-Maximilians - University of Munich
Collaborators:
Maastricht University Medical Center
UMC Utrecht
University of Edinburgh
University of Oxford
Treatments:
Amlodipine
Atenolol
Losartan