Effects of Anaesthesia on Inflammatory Markers

• Status: Recruiting
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

undertake confidently both open and laparoscopic cholecystectomy. Major types of body injuries surgical or accidental; evoke a temporary, yet predictable systemic inflammatory response caused by hormonal, immunological and metabolic mediators. This inflammatory response is essential for tissue repair and has evolved to maximize the organisms' healing potential. In healthy individuals the inflammatory response to major surgery is well balanced consisting of pro- and anti-inflammatory mediators. The severity of injury, the occurrence of surgical complications and its accompanying level of stress may hinder the balance of the inflammatory response6.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Lidocaine; Morphine

Criteria

Inclusion Criteria:

• Adult patients aging 18 - 55 years old

• Patients scheduled for abdominal surgeries

• Patients with American Society of Anesthesiologists (ASA) I, II physical status

Exclusion Criteria:

• Patients' refusal.

• Critically ill patients.

• Patients who have contraindications to regional anesthesia.