Overview

Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI

Status:
Unknown status
Trial end date:
2016-08-01
Target enrollment:
Participant gender:
Summary
To determine the acute and chronic effects of a short course of treatment on spinal cord injured (SCI) individuals with either an anticholinergic agent (tiotropium) or with a β₂ agonist (Salmeterol) on: - Fraction of expired NO (FeNO) - Selected Biomarkers of inflammation in exhaled breath condensates (EBC) - Pulmonary function, as measured by pulmonary function tests and body plethysmography
Phase:
Phase 1
Details
Lead Sponsor:
James J. Peters Veterans Affairs Medical Center
Collaborator:
Kessler Institute for Rehabilitation
Treatments:
Cholinergic Antagonists
Salmeterol Xinafoate
Tiotropium Bromide