Effects of Atorvastatin on Endothelial Progenitor Cells After Coronary Surgery
Status:
Completed
Trial end date:
2010-10-01
Target enrollment:
Participant gender:
Summary
Experimental data have demonstrated favourable effects of statins on endothelial progenitor
cell (EPC) mobilization from the bone marrow, and cardiac homing. The purpose of the present
prospective randomized controlled trial is to determine the effects of aggressive
atorvastatin treatment (40 mg daily 2-weeks prior to surgery) on the number of endothelial
progenitor cells (EPCs) after cardiopulmonary bypass by comparing with placebo.