Effects of Botulinum Toxin Injection on Sensation and Postural Control in Children With Hemiplegic Cerebral Palsy

• Status: Recruiting
• Trial end date: 2021-09-01
• Target enrollment: 0
• Participant gender: All

Summary

In this study, the investigators aimed to investigate the effects of botulinum neurotoxin type A (BoNT-A) injection applied to the ankle plantar flexor muscles on lower extremity sensation and quantitative balance parameters in children with spastic hemiplegic cerebral palsy who are ambulatory without an assistive device in daily life.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Marmara University
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A

Criteria

Inclusion Criteria:

• Patients diagnosed with hemiplegic cerebral palsy

• Age between 5-13 years

• MAS ≥ 2 spasticity in the affected ankle

• Gross Motor Function Classification System (GMFCS) level I-II

• Able to understand given commands

• Sufficient cooperation to understand instructions and participate evaluations

• Giving an informed consent

• Botulinum toxin A injection decision made by an experienced Physiatrist

Exclusion Criteria:

• Visual, vestibular and cognitive deficits

• Botulinum toxin A treatment within 6 months or having undergone an orthopaedic surgery 1 year prior to inclusion in the study

• Presence of fixed contracture or joint instability in the affected ankle

• Severe scoliosis (Cobb angle >40°)

• Uncontrolled epilepsy

• Having undergone selective dorsal rhizotomy