Effects of Buprenorphine/Naloxone Administered in Different Ways For Treating Opioid Dependence

• Status: Completed
• Trial end date: 1998-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Buprenorphine is a treatment for opioid dependence. Naloxone is given in addition to buprenorphine in order to limit the abuse potential that is commonly associated with buprenorphine. The purpose of this study is to examine the effects of buprenorphine/naloxone when given through different routes and at different doses.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Buprenorphine; Buprenorphine, Naloxone Drug Combination; Naloxone

Criteria

Inclusion Criteria:

• Currently opioid dependent

• In good health, as determined by a pre-participation medical examination

• Seeking and eligible for methadone maintenance or detoxification treatment

Exclusion Criteria:

• Significant medical or psychiatric illness, other than drug dependence