Effects of Cariprazine on Cardiac Repolarization in Patients With Schizophrenia

• Status: Completed
• Trial end date: 2012-02-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the effects of sequential multiple dose regimens of cariprazine on cardiac repolarization in patients with schizophrenia.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Forest Laboratories
• Treatments: Cariprazine; Fluoroquinolones; Moxifloxacin; Norgestimate, ethinyl estradiol drug combination; Risperidone

Criteria

Inclusion Criteria:

• Men or women, age 18 to 50, inclusive

• Symptoms of schizophrenia or schizoaffective disorder first appearing a minimum of 1 year before screening

• Negative pregnancy test

• Normal physical examination results, vital signs, and clinical lab test results

Exclusion Criteria:

• Axis II disorder severe enough to interfere with the study

• Smoking more than 20 cigarettes a day

• History or presence of cardiovascular disorder

• Pregnant/breast-feeding and/or planning to become pregnant/breast-feed

• Imminent risk of injuring self or others or causing significant property damage