Effects of Cisatracurium on Succinylcholine-induced Fasciculations and Myalgia

• Status: Completed
• Trial end date: 2014-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the effects of different doses of cisatracurium pretreatment on succinylcholine-induced fasciculations and postoperative myalgia.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Yangzhou No.1 People's Hospital
• Treatments: Atracurium; Cisatracurium; Succinylcholine

Criteria

Inclusion Criteria:

• American Standards Association (ASA) physical status I or II patients scheduled for elective laparoscopic cholecystectomies with tracheal intubation requiring general anesthesia

• 20 - 65 years old

• without acid-base imbalance and electrolyte disturbance

• with normal hepatic and renal function

Exclusion Criteria:

• Patients with known hyperkalemia

• Patients with increased intraocular pressure

• Patients with increased intracranial pressure

• Patients with symptoms of gastroesophageal reflux

• Patients with anticipated airway difficulties

• Patients with malignant fever

• Patients with neuromuscular disease

• Patients with burn or crush injuries

• Patients with taking drugs known to alter the action of neuromuscular blockers

• Patients with with a body mass index exceeding 30